Iranian President Masoud Pezeshkian has said Iran will pursue negotiations with the US after requests from 'friendly governments in the region' to respond to a US proposal for talks. In a statement on X, Pezeshkian said he had told Iran's Minister of Foreign Affairs Abbas Araghchi to pursue talks 'provided that a suitable environment exists - one free from threats and unreasonable expectations'. The Iranian president's words come after the country's supreme leader Ayatollah Ali Khamenei warned any attack on Iran would spark a regional conflict. US President Donald Trump has threatened to intervene in Iran over its nuclear ambitions and deadly crackdown on protesters, building up forces nearby. 'These negotiations shall be conducted within the framework of our national interests', Pezeshkian added. The talks will be held in Istanbul on Friday, according to US media reports. Pezeshkian's announcement follows an interview with Araghchi in which he told CNN he was 'confident that we can achieve a deal'. Speaking to a press pool in the White House, Trump said on Monday 'if we can work something out' that would be 'great', but warned that 'bad things would happen' if not. The US carried out targeted strikes on Iran's nuclear facilities last year in what it called Operation Midnight Hammer. The strikes followed a large-scale operation by Israel to target Iran's facilities and nuclear scientists. Trump added that there was a 'tremendous force' headed to Iran, including the 'biggest and the best' ships. It follows a crackdown by Iranian security forces that protesters said was unlike anything they had witnessed before. Iranian authorities said that 3,117 people were killed during the protests, but activist and monitoring groups indicate the toll is significantly higher. US-based Human Rights Activists News Agency (HRANA) confirms the deaths of 6,430 protesters, while Norway-based Iran Human Rights (IHR) suggests the final toll could exceed 25,000. The widespread demonstrations were sparked by economic frustrations but evolved to include demands for political change. Iranian officials have informed Khamenei that public anger following these protests has reached a level where fear is no longer a deterrent.