President Trump’s decision to withdraw from the WHO raises alarms among health professionals, who fear that dismantling oversight of smallpox could lead to dangerous consequences, including weaponization concerns and a lapse in research safety.
Departure from WHO Sparks Concerns Over Smallpox Safety

Departure from WHO Sparks Concerns Over Smallpox Safety
Health experts warn that the U.S. exit from the World Health Organization jeopardizes smallpox virus management and international safety protocols.
In a move that has sent shockwaves through the global health community, President Trump’s directive to withdraw the United States from the World Health Organization (WHO) has raised serious concerns regarding the management of the smallpox virus. Experts assert that this retreat could unravel decades of international collaboration aimed at ensuring the safety and security of a pathogen that once caused untold human suffering.
Health officials warn that the cessation of WHO oversight jeopardizes stringent safeguards designed to prevent the accidental release of the smallpox virus, as well as hindering critical research efforts focused on developing effective countermeasures against the disease. Some experts also fear that without WHO oversight, there may be increased suspicions among nations, leading to concerns about the potential weaponization of smallpox.
Dr. Thomas R. Frieden, former director of the Centers for Disease Control and Prevention (CDC), expressed grave concerns, likening the secure labs storing the smallpox virus to a submarine in a building, complete with strict protocols for personnel who work with the virulent pathogen. He emphasized the importance of transparency and inspection to mitigate risks.
In a recent blog post for the Infectious Diseases Society of America, Dartmouth medical professor Daniel R. Lucey echoed these sentiments, warning that the implications of America’s withdrawal from the WHO could significantly undermine existing protocols for smallpox virus storage, experimentation, and reporting.
Historically, the WHO accomplished the monumental task of eradicating smallpox from human populations over fifty years ago, a feat hailed as a remarkable achievement in both medical science and global cooperation. Currently, two secure repositories exist – one in Atlanta and another in Russia – to conduct ongoing research should the virus ever re-emerge. These facilities adhere to stringent Biosafety Level 4 standards, the highest level of containment available.
As the world grapples with the implications of the United States distancing itself from international health commitments, experts are increasingly worried about the possible ramifications for the future of smallpox research and global health security.
Health officials warn that the cessation of WHO oversight jeopardizes stringent safeguards designed to prevent the accidental release of the smallpox virus, as well as hindering critical research efforts focused on developing effective countermeasures against the disease. Some experts also fear that without WHO oversight, there may be increased suspicions among nations, leading to concerns about the potential weaponization of smallpox.
Dr. Thomas R. Frieden, former director of the Centers for Disease Control and Prevention (CDC), expressed grave concerns, likening the secure labs storing the smallpox virus to a submarine in a building, complete with strict protocols for personnel who work with the virulent pathogen. He emphasized the importance of transparency and inspection to mitigate risks.
In a recent blog post for the Infectious Diseases Society of America, Dartmouth medical professor Daniel R. Lucey echoed these sentiments, warning that the implications of America’s withdrawal from the WHO could significantly undermine existing protocols for smallpox virus storage, experimentation, and reporting.
Historically, the WHO accomplished the monumental task of eradicating smallpox from human populations over fifty years ago, a feat hailed as a remarkable achievement in both medical science and global cooperation. Currently, two secure repositories exist – one in Atlanta and another in Russia – to conduct ongoing research should the virus ever re-emerge. These facilities adhere to stringent Biosafety Level 4 standards, the highest level of containment available.
As the world grapples with the implications of the United States distancing itself from international health commitments, experts are increasingly worried about the possible ramifications for the future of smallpox research and global health security.