Dane portrays Cal Jacobs, the father in the Jacobs family on HBO's acclaimed teen drama "Euphoria," which is set to kick off production for its third season shortly. Before his success in "Euphoria," Dane was celebrated for his role as Dr. Mark Sloan in "Grey's Anatomy" and has also starred in series such as "Charmed" and "The Last Ship." He has appeared in popular films like "Marley & Me," "Valentine's Day," and "Burlesque." Dane is married to actress Rebecca Gayheart, and they share two children.

ALS, known as Lou Gehrig's disease, is characterized by the gradual degeneration of motor neurons, which control muscle movements. Symptoms often begin with muscle twitching or weakness in limbs and can progress to affect speech, eating, and breathing. Currently, there is no cure for ALS, with life expectancy averaging three to five years post-diagnosis for most patients, although some may survive longer.