Tragic UPS Cargo Plane Crash Claims Seven Lives in Kentucky

Wed Nov 05 2025 11:04:36 GMT+0200 (Eastern European Standard Time)

A UPS cargo plane crash during takeoff from Louisville Muhammad Ali International Airport has resulted in at least seven fatalities and numerous injuries, prompting a major emergency response.

A UPS cargo plane tragically crashed while taking off from Louisville, Kentucky, killing at least seven individuals and injuring over eleven others. The incident, which involved an explosion and significant damage to nearby businesses, has led to an ongoing investigation by the National Transportation Safety Bureau.

Seven people were killed when a UPS cargo plane crashed while taking off from an airport in Louisville, Kentucky on Tuesday evening, the state's governor said.

At least 11 other people were injured when the freight plane exploded as it departed Louisville Muhammad Ali International Airport at around 17:15 local time (22:15 GMT), sending thick plumes of black smoke into the sky.

Kentucky Governor Andy Beshear said the plane's three crew members were likely to be among the dead, adding that, Anyone who has seen the images and the video knows how violent this crash is.

Officials warned that people suffered very significant injuries in the incident and the death toll could rise.

UPS flight 2976 bound for Honolulu, Hawaii was carrying 38,000 gallons (144,000 litres) of fuel when it skidded off the runway in Louisville and struck nearby buildings.

The explosion engulfed at least two nearby businesses, including a petroleum recycling company. A shelter-in-place order was initially issued for within five miles of the airport due to concerns of further explosions and air pollution, but was later reduced to just one mile.

All departing flights for Tuesday evening were cancelled, the airport said in a statement on X.

Louisville Fire Dept Chief Brian O'Neill said the fire has almost entirely been contained, with crews still deployed at the crash site.

He added: When you have such a large scale incident and fire that spread over such a massive area, we have to use hundreds of personnel to surround it, contain it, and then slowly bring it in.

The aircraft was a MD-11F, a triple-engine jet that started service 34 years ago with Thai Airways as a passenger jet, but was transferred to UPS in 2006. In a statement, Boeing said it is ready to support our customer and that our concern is for the safety and well-being of all those affected.

Louisville is home to UPS Worldport, a global hub for the delivery firm's air cargo operations and its largest package handling facility in the world. Louisville Mayor Craig Greenberg called the crash an incredible tragedy that our community will never forget.