Adrianzén's departure, marking the third prime minister to resign under President Dina Boluarte’s leadership, significantly complicates an already volatile political landscape. By constitutional mandate, Adrianzén’s resignation necessitates the dismissal of all cabinet ministers, thus forcing President Boluarte to overhaul her entire executive team. Although she retains the authority to reappoint former ministers, this reshuffling can only take place after a new prime minister is appointed.

The resignation arises during a particularly tumultuous period as public discontent grows over escalating crime rates and ineffective governance. Protests have erupted across the country, with citizens, dressed in white, calling for urgent action against extortion and gang violence that heavily affect daily life and local businesses. President Boluarte's approval ratings have plummeted since her inauguration, following the impeachment of her predecessor, Pedro Castillo. Recent cabinet changes, which introduced new ministers for finance, interior, and transport, have now become moot as those appointed just hours prior are also required to resign.

Peru now faces uncertainty not only in leadership but also in addressing the rising security crisis that citizens believe is being left unchecked by the government.