A cohort of pediatricians and toxicologists has submitted a report questioning the validity of insulin tests crucial to Lucy Letby’s conviction, sparking discussions about potential miscarriages of justice as her legal team seeks to open an appeal.
Concerns Rise Over Insulin Test Validity in Lucy Letby Case

Concerns Rise Over Insulin Test Validity in Lucy Letby Case
Experts challenge the reliability of key evidence in the conviction of a nurse accused of multiple infant murders.
A new report by a group of seven pediatric doctors and toxicology experts has sparked significant debate concerning the conviction of Lucy Letby, a nurse sentenced to 15 life terms for the murder of seven newborns at a British hospital. On April 3, 2025, Letby’s lawyer presented evidence to the Criminal Cases Review Commission, which investigates possible miscarriages of justice, asserting that the insulin tests cited by prosecutors during her trial were fundamentally flawed.
Letby was declared guilty in 2023 of various criminal actions against infants, including injecting air, overfeeding, and poisoning with insulin. The experts' report challenges the integrity of the insulin poisoning evidence presented to the court, with one toxicologist and other medical professionals deeming it "unreliable." Their critique emphasized that this evidence casts doubt on the prosecution's claims regarding insulin and C-peptide testing, which were pivotal in securing Letby’s conviction.
Letby has consistently maintained her innocence throughout the process, and ongoing scrutiny has amplified calls for a re-examination of the case, especially following a detailed article published in the New Yorker that raised additional questions about her guilt. Despite efforts initiated by her legal representatives to appeal the ruling, earlier attempts to reopen the case had been thwarted. The forthcoming review by the Criminal Cases Review Commission is now watched closely as it determines the fate of Letby’s potential appeal.